www.med.upenn.edu/apps/faculty/index.php/g275/p16258

Gwenn-ael Danet-Desnoyers, Ph.D. was appointed in 2002 as a Research Assistant Professor of Medicine at the University of Pennsylvania, School of Medicine. Dr. Danet was also appointed as Technical Director of the Stem Cell and Leukemia Core at the University of Pennsylvania Cancer Center. Prior to these appointments, he was an Instructor at the University of Pennsylvania, School of Medicine and at the Pritzker School of Medicine at the University of Chicago, and a Fellow of the Howard Hughes Medical Institute. Dr. Danet's research focuses on the characterization of human hematopoietic stem cells and the cellular and molecular mechanisms that underlie their transformation to leukemic stem cells. He recently reported the characterization of a novel human stem cell population with both hematopoietic and hepatic potential (Proc. Natl. Acad. Sci. USA, 2002; 99, 10441), and described how hypoxia can regulate human hematopoietic stem cells in bone marrow (J. Clin. Invest. 2003; 112, 126). He is an expert in the field of xenotransplantation of human cells in immune-deficient mice for the study of primary normal and leukemic stem cells. He recently filed a patent for the use of C1qRp as a new marker for the isolation of all human hematopoietic stem cells.